Principal Scientist, Cheminformatics (Small Molecule & DEL Informatics)
$115k/y-$197.8k/y
2 days ago
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HybridFull-timeMid
Summary
Johnson & Johnson Innovative Medicine is seeking a Principal Scientist, Cheminformatics to join their team in Spring House, PA, Cambridge, MA, or San Diego, CA. The role focuses on developing advanced cheminformatics tools and supporting small molecule informatics capabilities.
About the Role
As a Principal Scientist in Cheminformatics, you will lead the development and implementation of cheminformatics tools for small molecule analysis and DEL informatics. You will collaborate with interdisciplinary teams, enhance internal ML virtual screening capabilities, and manage contractors to ensure project delivery. Your work will involve designing computational workflows and staying updated on industry trends to improve project outcomes.
About You
Required:
- PhD in Cheminformatics, Chemical Engineering, Computational Chemistry, or a related field.
- Minimum of 3 years of industry experience with a proven track record of delivering end-to-end solutions from conceptualization to implementation.
- Deep expertise in cheminformatics software (e.g., KNIME, OpenEye) and programming languages (e.g., Python, R).
- Expertise in structure-activity relationship (SAR) analysis.
- Experience working in cross-functional teams & translating ideas from bench scientists to informatics solutions.
- Excellent problem-solving and communication skills with a collaborative mindset.
Preferred:
- Good knowledge of DNA-encoded libraries and their applications in drug discovery.
- Experience with statistical analyses and machine learning techniques applied to chemistry problems.
- Experience managing contractors or direct reports.
- Experience leading strategic initiatives.
- Experience in dashboarding (e.g., Spotfire, streamlit, shiny).
- Familiarity with medicinal chemistry end-user tools (e.g., LiveDesign).
Benefits
- Competitive base pay range of $115k–$198k with eligibility for an annual performance bonus.
- Comprehensive benefits package including medical, dental, vision, life insurance, and disability coverage.
- 401(k) retirement plan and savings plan.
- Vacation up to 120 hours per calendar year and sick time up to 40 hours per calendar year.
- Holiday pay including up to 13 days per calendar year.
Johnson & Johnson Innovative Medicine
At Johnson & Johnson Innovative Medicine, we innovate with purpose, to lead where medicine is going. The experiences of patients around the world inform and inspire our science-based innovations, which continue to change and save lives. Applying rigorous science with compassion, we confidently address the most complex diseases of our time and develop the potential medicines of tomorrow. We are continuously working to develop treatments, aspiring to find cures, pioneering the path from lab to life, and championing patients every step of the way. https://bit.ly/3reuMvK
Cambridge, MA